EFFICACY OF ACNE VULGARIS TREATMENT PROTOCOLS ACCORDING TO ITS CLINICAL FORMS

EFFICACY OF ACNE VULGARIS TREATMENT PROTOCOLS ACCORDING TO ITS CLINICAL FORMS

Etleva Jorgaqi

 

Irena Savo

 

Andi Koraqi

 

Xiliola Doci

 

Rozana Cela

 

Ermira Vasili

 

Mohammad Jafferany

First published: May 17, 2020

 

https://doi.org/10.1111/dth.13611

 

https://onlinelibrary.wiley.com/doi/abs/10.1111/dth.13611

Summary: To compare the results of different treatment regimens based on acne stratification to prescribe the appropriate treatment protocol according to the clinical form and degree of acne. A cross-sectional, cohort study conducted in 230 patients with acne vulgaris. Patients were divided into three groups according to acne severity, and the results of each protocol were determined at 0, 4, 6, 8, 12, 18, and 24 weeks. Statistical analysis was performed using Wilcoxon and Mann-Whitney tests 230 patients (99 women and 131 men) participated in the study. In grade 1 acne (70 patients), the most effective drug for papulo-pustular lesions was azelaic acid, with a mean reduction of 1.03% per week. For comedone reduction, the most effective drug was retinol with an average reduction of 17.7% per week. In grade 2 acne (66 patients), the most effective regimen was: doxycycline + topical retinoid + benzoyl peroxide. In the third class (92 patients), the most effective drug was oral isotretinoin. Accurate stratification based on clinical characteristics is necessary for a better outcome. The success of the treatment is related to the respective treatment schemes individually adapted to the acne patients.